Colorectal cancer is the #2 cause of cancer deaths in the U.S.—and by 2030, it’s expected to be the #1 killer for people under 50.

Enter Cologuard: the at-home colon cancer screening test. You literally poop in a box, ship it to a lab, and boom—life-saving results. Weird? Yes. Important? Absolutely.

Cologuard tapped us to break the stigma with a viral campaign aimed at diverse 45–50-year-olds. Our answer? Get Low #2—a full-blown remix of Lil Jon’s crunk classic, turning a taboo topic into a cultural moment.

Case Study

Music Video

Activation

In Atlanta, we teamed up with the Falcons and Lil Jon for a tailgate takeover—golden “Little Johns,” 360° dance cam, and a GET LOW dance battle.

Cologuard took over the stadium with signage inside and out—capped by Lil Jon dropping a 90-second “Get Low #2” on the field during a timeout.

VH1 Flashback

Every 45–50 year old remembers VH1’s Pop-Up Video—so we made our own “Poop-Up” version, mixing colon cancer facts, a Cologuard intro, and behind-the-scenes nuggets from the shoot.

Press